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GenoDiverse-Benefits

Maximizing genetic variation within plant species, a necessary condition to introduce novel traits.

Reducing the risk of losing rare but valuable genetic variants.

Identifying valuable pre-breeding material in wild or landrace populations.

Accelerating breeding progress by facilitating the selection of complementary parental lines.

Providing polymorphic markers ready-to-use in marker-assisted selection programs.

GenoDiverse-Deliverables

Genotyping Platform Strategy

We recommend strategies of genotyping platform based on your budget and specific needs. We guide you on selecting the most suitable genotyping technology, such as SNP arrays, SSR analysis, or targeted sequencing, considering factors like cost-effectiveness, throughput, and resolution.

Genetic Diversity Report

We deliver a comprehensive report that describing the genetic diversity within your breeding population. By using visual aids such as dendrograms, heatmaps, cluster groups, and diversity scores, the report will provide a detailed analysis of genetic relationships, population structure, and diversity indices. These tools offer clear insights into the distribution of genetic variation into your genetic pool and help in making informed decisions about your breeding strategies.

Polymorphic Marker or Haplotype Identification

We deliver a curated list of polymorphic markers or haplotypes around the genes of interest for your breeding program. These markers or haplotypes are associated with favorable genetic variants, allowing for efficient marker-assisted selection.

Genetic Variation Utilization Strategy

We recommend strategies for optimizing the utilization of genetic variation in your breeding program. It may include recommendations for parental selection, mating designs, and allele introgression. By this way we expect to help you in enhancing trait expression and accelerating breeding progress.

GenoSelection-Benefits

Increasing the precision in selection by targeting genes or genomic regions associated with those traits.

Allowing Early Trait Detection at the seed or seedling stage, saving time and resources.

Providing higher selection accuracy especially for traits whose expression is influenced by environmental factors or they are assayed by challenging protocols .

Accelerating breeding progress by enhancing selection accuracy and efficiency.

GenoSelection-DELIVERABLES

Comprehensive Literature Report

We review in-depth public information about the genetic control of the trait of interest. By this report you will be able to understand the underlying genetic mechanisms and adapt the adequate targeted marker strategies.

Marker Development Strategy

We develope assays for published molecular markers or conducting de novo discovery of trait-marker associations. This strategy may involve QTL analysis, GWAS, or other advanced genomic techniques to identify markers linked to both simple Mendelian traits and complex polygenic traits.

Genetic Maps

We generate genetic maps that illustrate the physical locations of molecular markers across the plant genome.

 Report of Marker-Trait Analysis

We report the identified markers, their genomic locations, and their associations with the trait of interest. Visual aids such as graphs and tables may be included to facilitate interpretation

Customized Trait-Marker Panels

 We design informative marker panels associated with a specific trait and validated in different breeding populations, securing available polymorphic markers for any cross of parental lines.

Marker-Assisted Selection (MAS) Recommendations

We recommend strategies for marker-assisted selection (MAS) programs based on the identified marker-trait associations.

GenoMetrics-Benefits

Heritability Estimation –  we accurately measures how much of a trait’s variation is genetic, guiding breeders in focusing on traits with higher genetic gain potential.

Optimized Experimental Design – we ensuresthat experiments are statistically sound, reducing errors and improving the reliability of results across trials and environments.

Validation of Genetic Models –  we confirms whether observed inheritance patterns follow expected genetic models (e.g. Mendelian genetics), ensuring the validity of breeding strategies.

Breeder’s equation – we predict genetic gain, optimize selection intensity, and improve long-term breeding efficiency by guiding decisions on which individuals to select for the next generation.

Correlation between traits –  wehelp breeders select one trait to improve another while balancing changes, since improving one trait might cause another to decrease.

 

GenoMetrics-DELIVERABLES

Trait Heritabilities

We calculate the trait heritability based on the available phenotypic data; then, we advise you how to design your breeding strategy, and give tips how to improve the heritability and increase the selection efficiency.

Experimental Design

We create an experimental design in way that minimises the effect of the environment. We achieve this by incorporting the appropriate number of replicates and blocks.

Breeder’s equation

We provide genetic gain predictions, optimized selection strategies and customized reports to help breeders make informed decisions.

Mendelian and Quantitative Traits

We study and report the genetic control of any trait, varying from simple mendelian to more complex traits. We identify the mendelian segregation ratios or generate the continuous distributions for more complex traits.

Trait correlations

We provide customized reports on trait relationships, indirect selection opportunities and multi-trait selection strategies.

GenoPrecision-Benefits 

Precise modification of target genes, minimizing off-target effects 

Versatility by the application to a wide range of plant species and traits.

 Sustainable solutions to pressing challenges in agriculture, such as disease resistance, climate resilience, and nutritional quality.

GenoPrecision-Deliverables

Candidate Gene Identification

We identify candidate genes by using advanced computational tools and databases. We base their selection on their known functions, expression patterns, and genetic associations with the target traits.

Causal Allele Analysis

We determine the causal alleles within the identified candidate genes responsible for the expression of the target traits. For this, we investigate allelic variations, single nucleotide polymorphisms (SNPs), insertions, deletions, and other genetic variations that directly influence trait expression.

Gene Editing Strategy Proposal

Based on the identified candidate genes and causal alleles, we propose tailored gene editing strategies for the client. This may include recommendations for CRISPR-Cas9 editing, EMS mutagenesis, or other gene editing techniques.

Candidate Sequence Design

We provide guidance on designing candidate sequences for CRISPR-Cas9 editing or EMS mutagenesis.

Final Report and Recommendations

The service concludes with the delivery of a comprehensive final report summarizing the candidate gene identification, causal allele analysis, gene editing strategy proposal, and sequence design recommendations.